Umjovo we-Dexamethasone
Ukwakheka
I-ml ngayinye iqukethe:
I-Dexamethasone sodium phosphate 2 mg.
Ama-excipients afika ku-1 ml.
Izincazelo
Uketshezi olucacile olungenambala.
Isenzo se-Pharmacological
Umuthi wenza isenzo sawo sekhemisi ngokungena futhi ubophezele kuphrotheni ye-cytoplasmic receptor futhi ubangele ushintsho lwesakhiwo ku-steroid receptor complex.Lolu shintsho lwesakhiwo luvumela ukuthuthela kwayo ku-nucleus bese ibophezela kumasayithi athile ku-DNA okuholela ekulotshweni kwe-m-RNA ethile futhi egcina ilawula ukuhlanganiswa kwamaprotheni.Inikeza isenzo se-glucocorticoid esikhethiwe kakhulu.Ivuselela ama-enzyme adingekayo ukunciphisa impendulo yokuvuvukala.
Izinkomba
Ukuphazamiseka kwe-Metabolic, izinqubo zokuvuvukala ezingatheleleki, ikakhulukazi ukuvuvukala kwe-musculoskeletal acute, izimo zokungezwani komzimba, ukucindezeleka nezimo zokushaqeka.Njengosizo ezifweni ezithathelwanayo.Ukwethulwa kokuzala kuma-ruminants ngesikhathi sokugcina sokukhulelwa.
Umthamo kanye nokuphatha
Ngomjovo we-intravenous noma we-intramuscular.
Izinkomo : 5-20mg (2.5-10ml) ngesikhathi.
Amahhashi: 2.5-5mg (1.25-2.5ml) ngesikhathi.
Amakati : 0.125-0.5mg (0.0625-0.25ml) ngesikhathi.
Izinja: 0.25-1mg (0.125-0.5ml) ngesikhathi.
Imiphumela emibi kanye ne-contraindication
Ngaphandle kokwelashwa okuphuthumayo, ungasebenzisi ezilwaneni ezine-nephritis engapheli kanye ne-hyper-corticalism (Cushing's Syndrome).Ukuba khona kokwehluleka kwenhliziyo eqinile, isifo sikashukela, kanye ne-osteoporosis yiziphambano ezilinganiselwe.Ungasebenzisi ezifweni ezibangelwa amagciwane ngesikhathi sesigaba se-viremic.
Isexwayiso
Kufanele kuqashelwe ukugwema ukuzijova ngephutha.
Uma ibhodlela seliphehliwe, okuqukethwe kufanele kusetshenziswe zingakapheli izinsuku ezingama-28.
Lahla noma yimuphi umkhiqizo ongasetshenzisiwe nezitsha ezingenalutho.
Geza izandla ngemva kokusebenzisa.
Isikhathi Sokuhoxiswa
Inyama: izinsuku ezingama-21.
Ubisi: amahora angama-72.
Isitoreji
Gcina endaweni epholile neyomile engaphansi kuka-30 ℃.
